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American Society of Microbiology ABMM Sample Questions (Q49-Q54):

NEW QUESTION # 49
Microscopic examination of a trichrome-stained stool smear reveals amoebic trophozoites approximately 25
µm in diameter, containing ingested red blood cells. The nucleus, when visible, has fine, evenly distributed peripheral chromatin and a small, central karyosome. These features are diagnostic for:

A. Entamoeba coli
B. Iodamoeba bütschlii
C. Endolimax nana
D. Entamoeba histolytica

Answer: D

NEW QUESTION # 50
A patient with HIV infection and a CD4+ T-cell count below 50 cells/µL develops a progressive neurological illness characterized by confusion, motor deficits, and seizures. Brain MRI reveals multiple white matter lesions without mass effect. PCR of the CSF is positive for JC virus. Thepathogenesis of this condition, progressive multifocal leukoencephalopathy (PML), involves:

A. Opportunistic infection by JC virus due to impaired cell-mediated immunity.
B. Direct cytopathic effect of JC virus on neurons.
C. Lytic infection of oligodendrocytes by JC virus, leading to demyelination.
D. Inflammatory demyelination triggered by JC virus infection of astrocytes.

Answer: C

NEW QUESTION # 51
A patient with HIV infection and a CD4+ T-cell count below 100 cells/µL presents with headache, fever, and altered mental status. CSF analysis reveals elevated protein and low glucose. India ink stain is negative.
Cryptococcal antigen test of the CSF is positive. The MOST appropriate initial treatment is:

A. Fluconazole
B. Amphotericin B and flucytosine
C. Caspofungin
D. Voriconazole

Answer: B

NEW QUESTION # 52
A research laboratory is studying the pathogenesis of respiratory syncytial virus (RSV) infection in infants.
They find that a specific viral surface glycoprotein is primarily responsible for attachment to host cells. This glycoprotein is:

A. Fusion protein (F)
B. Hemagglutinin (H)
C. Neuraminidase (N)
D. Matrix protein (M)

Answer: A

NEW QUESTION # 53
A clinical microbiology laboratory is implementing a new quality control procedure for blood culture media.
To ensure the media supports the growth of a wide range of clinically significant organisms, they should include:

A. Only antibiotic-resistant control strains.
B. A diverse panel of fastidious and non-fastidious bacteria and yeasts.
C. Only control strains that are commonly found as contaminants.
D. Only Gram-positive and Gram-negative control strains.

Answer: B

NEW QUESTION # 54
......

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